INHIBITION OF P-GLYCOPROTEIN BY HIV PROTEASE INHIBITORS INCREASES INTRACELLULAR ACCUMULATION OF BERBERINE IN MURINE AND HUMAN MACROPHAGES.

Inhibition of P-glycoprotein by HIV protease inhibitors increases intracellular accumulation of berberine in murine and human macrophages.

BackgroundHIV protease inhibitor (PI)-induced inflammatory response in macrophages is a major risk factor for cnd shellac spring 2023 cardiovascular diseases.We have previously reported that berberine (BBR), a traditional herbal medicine, prevents HIV PI-induced inflammatory response through inhibiting endoplasmic reticulum (ER) stress in macrophag

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In vitro assessment of the anthelmintic activity of copper oxide and zinc oxide nanoparticles on egg and adult stages of Fasciola hepatica: evidence on oxidative stress biomarkers, and DNA damage

Abstract Objectives Fasciolosis is of significant economic and public health importance worldwide.The lack of a successful vaccine and emerging resistance in flukes to the drug of choice, triclabendazole, has initiated the search for exhaust tips for chrysler 300 alternative approaches.In recent years, metallic nanoparticles have been extensively i

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